There are many fat-dissolving devices, technologies, and procedures available to reduce fat. Mesotherapy is the term used to describe the injection of substances to cause fat inflammation and destruction. The name brand and most popular mesotherapy right now is Kybella. This treatment is FDA approved to treat submental fat which is the fat under the chin. Multiple treatments may be necessary. At Retief Skin Center, we use the Exilis Elite and Facetite devices for fat reduction.