Perlane: FAQ

How is Perlane different from Restylane?

Both Perlane and Restylane are composed of hyaluronic acid. The primary difference between Restylane and Perlane is that the hyaluronic acid gel particles in Perlane are larger than those found in Restylane. This gives Perlane additional ability to lift and fill the areas of injection that require a denser formulation. Perlane and Restylane are perfect complements to one another.

How do Perlane and Restylane work?

Perlane® is injected into the skin to smooth away wrinkles and folds. Perlane®’s water-loving nature attracts and binds water molecules to help maintain volume.

Perlane® is composed of hyaluronic acid, a natural substance that already exists in the body. The hyaluronic acid in Perlane® is a crystal clear gel that is chemically cross-linked (the long chemical strands are tied together) to delay breakdown by skin enzymes. Perlane® is non-animal-based and free from animal protein. This quality prevents disease transmission. Allergy pre-testing is not necessary. Also distinct from other hyaluronic acid dermal fillers, Restylane and Perlane are minimally cross-linked, making them similar to the natural hyaluronic acid found in the body. Also view the Restylane-Perlane website.

Can Perlane be used in tandem with other fillers?

Dr. Retief finds that most facial correction needs beyond superficial lines will be restored most naturally by the use of product layers. Perlane is the ideal “middle layer” for deep folds. Beginning with Radiesse in the very deep skin layer, Dr. Retief will add Perlane as a topper.

For other wrinkles or folds, Perlane may be chosen as the support layer with Restylane or Juvederm used as the top product. Depending on the level of correction needed, Dr. Retief will recommend the most advantageous combination.

Patients who find themselves with deep folds and superficial lines may even use three filler layers, such as Radiesse as a base, Perlane as the pillow top and Belotero to smooth the small vertical and smokers’ lines that require placement directly below the uppermost layer of the skin.

BrianPerlane: FAQ